Juventus boss Maurizio Sarri will be unable to call upon three first-team players as Sami Khedira, Alex Sandro and Mattia De Sciglio all miss out with injuries. Danilo is back in contention after having served his one-match suspension.
The big headline ahead of the game, though, is that star midfielder Miralem Pjanic has signed for Barcelona, with Arthur Melo moving to Juventus. Both the players will continue playing for their current clubs till the season is over. Sarri should continue with his preferred 4-3-3 system, with Wojciech Szczesny lining up between the sticks for the champions.
Juan Cuadrado should continue at right-back, while the returning Danilo should walk right back into the starting XI, slotting in on the left side of the defence. Matthijs de Ligt, who scored in the last game, should continue to pair up with Leonardo Bonucci at the heart of the backline.
Pjanic, despite his current situation, should continue at the base of the three-man midfield and look to dictate the tempo of the game. Rodrigo Bentancur is likely to be retained in the centre of the park, while Blaise Matuidi should return to midfield, after starting at left-back last time out. Adrien Rabiot drops out to the bench.
Paulo Dybala and Cristiano Ronaldo were both on the scoresheet against Lecce in the previous match and should start against Genoa. The former will operate centrally, with Ronaldo on the left while Federico Bernardeschi should feature on the right flank.
Probable Lineup (4-3-3): Szczesny; Cuadrado, de Ligt, Bonucci, Danilo; Bentancur, Pjanic, Matuidi; Bernardeschi, Dybala, Ronaldo